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Shive W, Pinkerton F, Humphreys J, Johnson MM, Hamilton WG, Matthews KS (1986) Development of a chemically defined serum- and protein-free medium for growth of human peripheral lymphocytes

3) Patient-level factors that shift risk at a given dose Ethanol (acute and chronic): Chronic use induces CYP2E1 more NAPQI

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The call will fund multinational, GCP-compliant Phase I, Phase I/II and Phase II interventional clinical trials in rare diseases, with the aim of generating robust clinical evidence and, where appropriate, data of regulatory relevance to support future regulatory interactions and clinical development