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Caloric restriction mimicry: Some investigators have noted that the metabolic effects of glutathione repletion in older adults improved insulin sensitivity, reduced inflammation, enhanced mitochondrial function overlap substantially with known benefits of caloric restriction, suggesting that glutathione deficiency may partly mediate the metabolic decline of aging [10][11]

There is limited information on the response of glutathione synthesis in human sepsis

Tissue damage from neutrophil-induced oxidative stress in COVID-19

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