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Importantly, we show that combination treatment is efficacious in chemo-naive tumours of varying grade and has the potential to increase survival even in an advanced tumour setting

This is where further workup becomes important

Benzyl alcohol has been associated with toxicity in premature infants, including the condition described in medical literature as "gasping syndrome" characterized by metabolic acidosis, respiratory distress, and central nervous system dysfunction

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Clinical deficiency with clearly low blood levels affects a smaller percentage, but a much larger group falls into a gray zone where levels are low enough to cause subtle symptoms without triggering an obvious diagnosis