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Useful soft tissue endpoints include: muscle fibre organisation vascular response inflammatory marker panels collagen deposition fibroblast activity oxidative stress markers histology scoring cell migration These research areas overlap with tendon and ligament studies but focus more broadly on tissue integrity and repair-associated signalling

721 , 722 , 723 , 724 , 725 , 726 More studies are also needed to adapt proven interventions or develop new intervention approaches for families from different racial, ethnic and socioeconomic backgrounds and in different geographic settings