FDA approval phases 1, 2, and 3 clinical trials requires companies to conduct large-scale studies to determine safety and efficacy
Abbreviations CMAP: Compound motor action potential CNS: Central nervous system ECM: Cone-extracellular matrix egr-1 gene : Early growth response-1 gene EMG: Electromyography FAK: Focal adhesion kinase GLP: Good laboratory practice HNE: 4-Hydroxynonenal HPLC: High-pressure liquid chromatography JAK-2: Janus kinase 2 LD1: Lethal dose 1 LTB4: Leukotriene B4 MPO: Myeloperoxidase MPTP: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine MUP: Motor unit potential naB2: Nerve growth factor 1-A binding protein-2 NSAIDs: Non-steroid anti-inflammatory drugs SCI: Spinal cord injury TXB2: Thromboxane B2 References Seiwerth S, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, et al
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