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Description

Phase Ib study design evaluating the safety, pharmacokinetics and pharmacodynamics of selnoflast, a novel NLRP3 inflammasome inhibitor in early-stage PD (P211.007)

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Bottom Line The FDA's July 2026 advisory meeting is a consequential regulatory moment one that has been building since the 2023 restrictions and has been accelerated by a political environment unusually sympathetic to the compounding industry and wellness sector

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Enabling dose escalation studies with 0.5mg or 0.25mg increments that oral formulations cannot match

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Transgenic inhibition of astroglial nf-kappa b improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation

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SmTGR is not stable in lower ionic strength buffers and was therefore prepared in 1X MAT (50 mM acetic acid, 50 mM MES, 100 mM Tris) buffer pH 7.4

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