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69 HayashiK.MorishitaR.NakagamiH.YoshimuraS.HaraA.MatsumotoK.et al (2001)

B., Bradfield, C

A four-week hold is roughly the window needed for a step to reach steady state and for the gut to adapt to it, which is why escalating before the block is complete effectively means judging a dose you have not yet fully experienced

G., He, W., Gibson, B