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J Biol Chem 287(12):89208931

Involvement of Nrf2 in myocardial ischemia and reperfusion injury

Arch Gen Psychiat 52: 805818

This interaction leads to the phosphorylation of the tyrosine residues of the Janus kinase-2 (JAK2) which mainly activates Signal Transducer and Activator Of Transcription (STAT), Rat sarcoma protein/Extracellular signal-regulated kinase (Ras/ERK) and phosphoinositide 3-kinase/Protein kinase B/AKT Serine/Threonine Kinase (PI3K/AKT) intracellular signaling pathways (5)