Pickart [3]: The molecule is very safe and no issues have ever arisen during its use as a skin cosmetic or in human wound healing studies. GHK-Cus biological actions appear to be health positive, hence its inclusion in a wide variety of cosmetic products such as hair growth serums, creams, lotions, and even dermal patches
It is associated with modulating sleep patterns, stress response, and endocrine regulation
Animal studies have examined its role in: Gastric ulcer models Intestinal mucosal injury Experimental colitis Inflammatory signaling Gut lining integrity Researchers have observed improved tissue stability and healing responses under controlled laboratory conditions
[1] Creatine is a naturally occurring compound synthesized in the liver, kidneys, and pancreas from amino acids (arginine, glycine, and methionine)
Together, they cover two different parts of repair biology: tissue signalling and cell movement