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People worldwide are smoking less and less cigarettes every year, while vapes and non-combustible products have earned additional market share only for Philip Morris

Kondo T, Hayashi M, Takeshita K, Numaguchi Y, Kobayashi K, Iino S, Inden Y, Murohara T: Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers

These pathways may contribute to synovitis, disturb synovium-cartilage crosstalk, and promote joint degeneration in susceptible individuals, although direct OA-specific evidence remains limited, particularly for EC exposure

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