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Here is a summary of how topical GHK-Cu was administered in three select studies: In a 1998 study by Abdulghani et al., GHK-Cu was found to have a significant effect on collagen production when applied as a cream to the thigh area for one month

(PubMed) There is also a more basic issue: even when these studies report health or survival benefits, they do not establish that the benefit was driven specifically by telomere extension

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Ans: The label lists a suggested dose of 5 mL per 100 pounds of body weight for calves, swine, and sheep

Proposed mechanisms include fibroblast migration and proliferation, modulation of growth-factor signalingincluding EGF and VEGFand changes in reticulin and collagen-fiber formation at injury sites