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The compound also appears to stimulate the production of decorin , a proteoglycan that helps organize collagen fibers and maintain skin structure

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Notable changes include increased ALT and AST and decreased levels of ALP, suggesting compromised liver function

A significant subsequent advance was the construction of a de novo physical map (~340 Mb) using BioNano Genomics, which enabled a hybrid assembly that nearly doubled the N50 to 697 kb and greatly improved genome continuity ( In a second phase, researchers used these resources to resequence cultivated accessions of A