Informed, evidence-based dialogue with patients remains essential, particularly in an era where public interest and commercial marketing have outpaced peer-reviewed data
The factors that lead to depletion of glutathione includes natural ageing process, or the external stressors that include chronic exposure to chemical toxins, cadmium exposure, alcohol use, smoking, pollution, strenuous aerobic activities, dietary factors, ultraviolet (UV) radiation exposure, tissue injury as from burns, ischemia, septic shock, surgery, drugs (such as acetaminophen and adriamycin)
GSH serves as the primary buffer against H 2 O 2
Further, co-occurrence of autoimmune atrophic gastritis with other autoimmune conditions, especially autoimmune thyroiditis and type 1 diabetes mellitus, has been reported (11, 12)
No human clinical trials in stroke or TBI populations have been published