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2017 Cell study used 5 mg/kg intraperitoneal injection three times per week in aged mice, with treatment periods of several weeks the three-times-weekly dosing suggests the peptide maintains sufficient functional concentrations for at least 48-72 hours per dose (PMID: 28340339)

Am J Physiol 270 L173L182 Avissar N, Eisenmann C, Breen JG, Horowitz S, Miller RK, Cohen HJ 1994 Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation

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doi:10.1111/j.1432-1033.1997.00273.x