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biologic gradient (dose-response evidence)

In Korea, Camel sought to establish the brand as the smoke of choice among discriminating infantrymen

SENECA SMOOTH MENTHOL 100s BOX (SENECA SMOOTH MENTHOL 100s BOX) SENECA SILVER 100s BOX (SENECA SILVER 100s BOX) SENECA MENTHOL 100s BOX (SENECA MENTHOL 100s BOX) SENECA FULL FLAVOR KING SIZE (SENECA FULL FLAVOR KING SIZE) SENECA FULL FLAVOR 100s BOX (SENECA FULL FLAVOR 100s BOX) SENECA CIGAR VANILLA (SENECA CIGAR VANILLA) SENECA CIGAR RED (SENECA CIGAR RED) SENECA CIGAR GREEN (SENECA CIGAR GREEN) SENECA CIGAR GRAPE (SENECA CIGAR GRAPE) SENECA CIGAR CHERRY (SENECA CIGAR CHERRY) SENECA CIGAR BLUE (SENECA CIGAR BLUE) SENECA BLUE KING SIZE (SENECA BLUE KING SIZE) SENECA BLUE 100s BOX (SENECA BLUE 100s BOX) LD SILVER 100s BOX (LD SILVER 100s BOX) LD RED KING SIZE BOX (LD RED KING SIZE BOX) LD RED 100s BOX (LD RED 100s BOX) LD MENTHOL GREEN 100s BOX (LD MENTHOL GREEN 100s BOX) LD MENTHOL 100s BOX (LD MENTHOL 100s BOX) LD BLUE KING SIZE BOX (LD BLUE KING SIZE BOX) LD BLUE 100s BOX (LD BLUE 100s BOX) CROWNS RED KING SIZE BOX (CROWNS RED KING SIZE BOX) CROWNS RED 100s BOX (CROWNS RED 100s BOX) CROWNS GREEN MENTHOL 100s BOX (CROWNS GREEN MENTHOL 100s BOX) CROWNS GOLD KING SIZE BOX (CROWNS GOLD KING SIZE BOX)

MMWR July 28, 2000

Emissions increased nearly linearly with puff duration, while puff flow had a relatively small effect