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More recently, it has been demonstrated that 1012 weeks of dietary supplementation with Endocalyx, which contains high-molecular weight HA and other glycocalyx components, restores the glycocalyx and ameliorates age-related vascular dysfunction in aged mice (135)

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The following antibodies were used: antibodies against human eNOS, phosphor-eNOS (Ser1177), Cav-1, phosphor-Cav-1 (Tyr14), Src and phosphor-Src (Tyr416) were obtained from Cell Signaling (MA, USA)