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The larger, longer trial failed to show significant results at all

doi: 10.1038/s41419-023-06045-y 92 MurphyMP

MOTS-c Purported Benefits: Improved insulin sensitivity Enhanced energy metabolism Potential anti-obesity effects Potential Risks and Complications: Metabolic Dysregulation: May cause hypoglycemia or hyperglycemia, leading to serious health issues

The estimate of liver necrosis is rather small, less that 0.05% damage, and this may be sufficient to account for the elevation of ALT observed by Watkins et al.[38], and the absence of symptoms of liver disease after chronic usage

Selenoprotein T (SELENOT) plays a crucial role in cardiomyocyte differentiation and protection, but its role in cardiomyocyte senescence remains unknown