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2021 Aug 20;12(1):5064

doi:10.1001/archinternmed.2008.574

Under the medical direction of Dr

In this study, we thoroughly investigated ACSL4/GPX4 and FSP1-mediated ferroptosis in oxalate-induced AKI, highlighting that targeting ferroptosis in renal tubular epithelial cells may be a promising strategy for treating and preventing the progression of this oxalate-induced nephropathy

Studies show that 3080% of infertile men exhibit elevated ROS levels, which attack and damage deoxyribonucleic acid (DNA) and the proteins and lipids of sperm [5], leading to compromised functionality, including interference with capacitation processes needed for successful fertilization [6,7]