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Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial

Refrigerate immediately once reconstituted, and use within 28 days

N-acetylcysteine treatment in chronic obstructive Pulmonary disease (COPD) and chronic bronchitis/pre-COPD: distinct meta-analyses

Neutrophils release myeloperoxidase (MPO) and ROS, exacerbating oxidative stress (101), while M1-like macrophages secrete further pro-inflammatory cytokines, establishing a chronic inflammatory niche (102)