One study showed that murine and human ILC2s express the 7 nicotinic acetylcholine receptor, a receptor for the tobacco component nicotine, and that nicotine agonists inhibit ILC2 cytokine production by decreasing Gata3 expression and dampening NF-kB pathway activation 33
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Number of yearly cancer deaths attributable to tobacco smoking, 2021 Footnote Smoking also causes cancers of the nasal cavity, paranasal sinuses and ovary (mucinous)
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