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However, the FDA has not yet approved it for weight loss, and long-term research remains limited
Thus, dietary supplement B 12 supplementation at 500 to 1000 g per day allows pernicious anemia and certain other defects in B 12 absorption to be treated with daily oral megadoses of B 12 without any correction of the underlying absorption defects
Long-Term Protocols: The most clinically relevant studies evaluated subcutaneous doses of 0.25 mg (250 mcg), 0.5 mg (500 mcg), and 1 mg (1,000 mcg) administered daily for 24 weeks