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Even when symptoms have quieted, this is when connective tissue is thought to be strengthening rather than just feeling better

The substitution wouldn't address the same research question

Androgen receptor and Wnt signaling operate as key stimulators of HF development in FGF5 KO sheep To explore the causes of increased wool and active hair-follicle density in FGF5 KO sheep, we tested the expression levels of testosterone and DHT that cause androgenetic alopecia in the skin tissue of the KO and control groups by ELISA

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Journal of cardiothoracic and vascular anesthesia, 2011