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Moreover, the NRF2 mRNA level showed a positive correlation with the mRNA level of antioxidant enzymes in these studies (Reference Jiang, Chen and Liu33Reference Chen, Feng and Jiang35)

Biotin supplements (taken at 5-10 mg/day) can interfere with thyroid labs and cause a false appearance of hyperthyroidism

This reduction in swim speed is consistently observed in both F0 and F1 adult transgenic fish carrying LMNA (E358K) and LMNA (R453W) variants, mirroring the established pathogenic roles of these variants in individuals with LMNA -related CMD and EDMD2

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Integrating flavonoids with gene therapy could pave the way for individualized treatment plans tailored to specific genetic mutations responsible for epilepsy, allowing for precise therapeutic interventions (Street et al., 2023)