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10.1152/ajpendo.1998.274.5.E817 317 TaskerP

doi: 10.1038/s41586-019-1785-z 97 SongXSunXOhSFWuMZhangYZhengWet al

In many cases, insurance may cover B12 shots if medically necessary

PowolnyAABommareddyAHahmERNormolleDPBeumerJHNelsonJBet al

However, in the pivotal Phase IIb trial, it failed to demonstrate statistically significant weight loss compared to placebo at the primary endpoint, leading the developer (Metabolic Pharmaceuticals Ltd.) to terminate the commercial program