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Role of metabolic H2O2 generation: redox signaling and oxidative stress*

However, in a more recent randomized, placebo-controlled study in 102 subjects, daily supplementation with 600 mg of lipoic acid (+/- 800 mg of vitamin E [-tocopherol]) for 16 weeks had no effect on fasting blood glucose, fasting blood insulin, or a measure of insulin resistance called the homeostatic model assessment of insulin resistance (HOMA-IR) index (59)

For d-g, I, box plots show median (centre line), 25 th -75 th percentile (box bounds), minimum to maximum values (whiskers), with all individual data points shown

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