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To minimise gastrointestinal risks: Take ibuprofen with or after food Use the lowest effective dose for the shortest duration necessary Avoid exceeding 1,200 mg daily (for over-the-counter use) unless advised by a clinician Consider gastric protection (e.g., proton pump inhibitors) if prolonged use is necessary or if risk factors for peptic ulceration exist, as per NICE guidance Maintain good hydration, particularly if experiencing Wegovy-related gastrointestinal effects Special considerations apply to certain groups: Pregnancy and breastfeeding : Ibuprofen should be avoided during pregnancy, particularly after 20 weeks, unless specifically advised by a doctor
Moreover, rapid freezing and lyophilization under controlled conditions can preserve both the liposome morphology and protein activity during storage
pH-sensitive polymeric vesicles for GOx/BSO delivery and synergetic starvation-ferroptosis therapy of tumor
Diabetes 53 (Suppl 1), S119S124 (2004)
