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Sfera et al

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Using HEK-293 adherent cells and K-562 suspension cells treated with varying concentrations of menadione or l-Buthionine Sulfoximine (BSO), two compounds known to affect total glutathione (GSH + GSSG) levels, we assayed the cells in separate assays and in a multiplex assay

Chemical penetration enhancers including propylene glycol, dimethyl sulfoxide (DMSO), and various terpenes increase GHK-Cu skin penetration by 2-4 fold, though potential irritation risks require careful optimization

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