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This applies to all routes of administration

Vernonia amygdalina , native to tropical Africa, is commonly known as bitter leaf due to its distinct bitter flavor, attributed to its anti-nutritional components such as alkaloids, saponins, tannins, and glycosides

These three work in a dynamic relationship where each nutrient helps the others perform better

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Norepinephrine plays an important role in this transition by enhancing astrocytic glycogenolysis and lactate production, which effectively supports the energy demand of attentive states [98]