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We [have] never observed responses to PI3K inhibitors in mouse models of pancreatic cancer, since this type of cancer rarely has PI3K mutations, he said

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STAT3 inhibitors reversed surgery-induced H-type vascularisation of the subchondral bone, significantly reducing vessel volume and number of vessels, and subchondral bone deterioration and cartilage loss were mitigated due to reduced angiogenesis

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