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This activation then stimulates PPARs, nuclear respiratory factors 1 and 2 (Nrf1/2), and estrogen receptor-related receptors (ERR), enhancing the expression and activity of TFAM (Fontecha-Barriuso et al., 2020

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Research shows that some people taking a PPI may benefit from magnesium supplementation if a deficiency is present, as confirmed by [a] physician. Meacham also emphasizes the importance of anyone with a known medical condition consulting their doctor before taking a dietary supplement