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461 During regeneration, TRIB1 downregulation permits NRF2 nuclear translocation, activating antioxidant response and fostering a conducive environment for hepatocyte proliferation

Figure 2 The core characteristics and mechanisms of candidalysin are well-defined: it exerts cytotoxicity by membrane insertion/lytication, activates pathways such as EGFR-MAPK and NLRP3 inflammasome to induce inflammation and damage in host cells, and targeted anti-infection strategies against this toxin have been summarized (Lortal et al., 2025)

Hence, we investigated fed-batch fermentation using glucose as the sole carbon and energy source

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