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One study reported that TBI with loss of consciousness influences Lewy body formation, pathogenesis of PD but does not result in dementia and AD (Crane et al., 2016

These interventions carry no pharmacological risk and have well-established long-term benefits for metabolic health, cardiovascular risk reduction, and psychological wellbeing

Effects of ketamine on postoperative pain after remifentanil-based anesthesia for major and minor surgery in adults: a systematic review and meta-Analysis