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The combination of a CDK4/6 inhibitor and an exportin 1 inhibitor can synergistically induce senescence in hepatocellular carcinoma cells, and the senolytic drug ARV-825 can effectively eliminate these senescent tumor cells

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In PK cells, membrane-bound gemcitabine generated through NK cell-based adoptive cell transfer (ACT) exerts anti-tumor effects in PANC 1 cells by modulating GSH levels released during cancer cell lysis (42)

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