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On the other hand, TIS can be induced by anticancer drugs and radiotherapy

The most commonly mutated genes are the potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11), ATP-binding cassette transporter, subfamily C, member 8 (ABCC8), and insulin (INS) genes

By acting on central amylin receptors in the area postrema and hindbrain, it promotes satiation, slows gastric emptying, and inhibits postprandial glucagon secretion

The role of the reactive oxygen species and oxidative stress in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults