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In comparison to patients on diet and placebo only, the patients treated with orlistat demonstrated a significant improvement in blood glucose concentrations, insulin resistance, waist circumference, total and low-density lipoprotein cholesterol (LDL-C), and blood pressure [35-37]

A large proportion of participants exhibited hormonal imbalances, with one-fourth of participants having elevated FSH, one-third elevated LH, and 74.9% increased estradiol

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