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10.1038/s41580-020-00322-w 17 ChangM.LiuR.ChenB.XuJ.WangW.JiY.et al (2025)

Results were expressed as international units per liter of sample (IU/L)

Semaglutide activates both Gs- and Gq-signaling pathways in GLP-1R-expressing hindbrain neurons, driving increases in the secondary messenger cyclic AMP (cAMP) that suppress feeding behavior and reduce total energy intake

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We thank the staff of the beamline X06SA at the Paul-Scherrer-Institute, Swiss Light Source (SLS), Villigen, Switzerland, and the staff of the beamline ID30B, European Synchrotron Radiation Facility (ESRF), Grenoble, France, for assistance during data collection