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S., Cross, T

The liver's high glutathione content reflects its central role in detoxification and metabolism

doi:10.2174/138161211796196954

NAD + is also a precursor to cyclic ADP-ribose (cADPR), a secondary signaling molecule generated by enzymes such as cluster of differentiation 38 (CD38) 7 , and it can be hydrolyzed by sirtuins, which deacetylate histones and regulate gene expression 7