Adegoke EO, Rahman MS, Pang MG
But when they get out of control, they lead to muscle damage, inflammation, and longer recovery times
While oral supplements exist, intravenous (IV) or intramuscular (IM) administration provides higher bioavailability , ensuring the body absorbs and utilizes the full dose efficiently
A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007
Adverse effects in repetitive transcranial magnetic stimulation prevention and management