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Vitamin E acts as a regulator of cellular metabolism, and its deficiency leads to anaemia, dysregulation of energy metabolism, irregular mitochondrial function, and tissue damage resulting from increased lipid peroxidation ( 7 Nutritional antioxidants and thyroid disease 7.1 Trace elements 7.1.1 Iodine An average adult body contains around 15 to 20 mg of iodine located predominantly in the thyroid gland, which performs an essential role in synthesizing thyroid hormones