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Originally developed for type 2 diabetes management, these medications have been authorised for weight management in individuals with obesity or those who are overweight with weight-related health conditions

This recognition encouraged preclinical studies aiming to investigate both mechanistic aspects and intervention strategies to characterize and target this biological axis in conditions affecting muscle, brain, the immune system, and metabolic diseases

Glossary Activin A a growth factor that stimulates synthesis and secretion of follicle stimulating hormone (FHS)

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