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Studies that used 1 mg/day in oral and intravenous trials did not show meaningfully better outcomes than lower doses, and higher doses were associated with more reports of headache, diarrhea, and gastrointestinal effects

Always follow up with sunscreen during the day, as kojic acid can make the skin more sensitive to UV rays

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Mariano, A

The validation set including the remission group was used to verify the effectiveness as a biomarker for the diagnosis of depression and determination of remission status