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Canales, B
Stroke, particularly ischemic stroke, is a leading cause of adult disability and death worldwide, characterized by the sudden interruption of cerebral blood flow and the subsequent cascade of energy failure, excitotoxicity, oxidative stress, and neuronal death [8487]
Cross sectional studies done to assess the association between body composition and stimulated GH release in healthy subjects show that, adult people (mean age 50 yr) have a lower peak GH response to secretagogues (clonidine and arginine), and females had a higher response to arginine when compared to males
By influencing these neurotransmitters, peptide DSIP can promote slow-wave sleep, regulate sleep-wake cycles, and modulate stress responses
The benefits appeared to be slightly stronger in healthy individuals (rather than those with medical problems), when single organisms were used (rather than combinations), and when the treatment duration was eight weeks or longer
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