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Since vitamin B12 is primarily found in animal products, those who avoid meat, dairy, or eggs may develop low B12 levels over time

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Some investigators have suggested that the uremia of CKD is associated with decreased GH signalling contributing to the state of hepatic GH resistance (74) ( Figure 4 )

doi:10.1038/mp.2012.33, PMID: 22525486 Anderson G, Maes M (2013) Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications