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This is because moderate to high intensity cardiovascular exercise and resistance-based workouts (e.g., three to four sets using ~ 620 repetition maximum loads) rely extensively on carbohydrate as a fuel source (1)

10.1017/s0043933910000711 [DOI] [Google Scholar] Kidd M

this effect may be due to interference with erythrocyte maturation

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however, in vivo, one could imagine that repeated 5FU exposures would drive selection of pre-existing niches of tumours cells that had higher mitochondrial functionality