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The released iron can be utilized for cellular processes, stored in the labile iron pool (LIP), or exported to the extracellular space via ferroportin (FPN), the only known mammalian iron exporter ( 2 + levels can trigger the Fenton reaction, in which Fe 2 + reacts with hydrogen peroxide to generate highly reactive hydroxyl radicals, leading to the accumulation of reactive oxygen species (ROS) and enhanced lipid peroxidation (Figure 1)

Antiepileptic drugs such as phenytoin or carbamazepine where subtherapeutic levels could precipitate seizures

Metal transport across biomembranes: emerging models for a distinct chemistry

Final classification depends on the committee's recommendation and the FDA's subsequent rulemaking

87 Thus, high GSH may reduce the mutation rate in genes encoding drug targets such as ribosomal proteins or DNA gyrase