[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Yang L, Li X, Tang H, Gao Z, Zhang K, Sun K
The skin is pinched to lift the subcutaneous tissue away from the muscle, and the injection is administered slowly to minimize discomfort
[11] [12] There is a potential risk of pancreatitis
Overall, multiple mechanisms including inflammation and reduced FA re-esterification likely explain the impaired buffering capacity in adipocytes during obesity that leads to the spillover of FAs, buildup of toxic lipid metabolites and allosteric regulators that suppress insulin action and increased hepatic glucose output, respectively (Figure 5)
Keep both compounds in separate, clearly labeled vials