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Studies suggest chamomile may help promote sleep quality (19,20) and that apigenin may have an effect, which may be brought about by binding to receptors in your brain that promote feelings of calm (21)

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Employing melatonin as an immunomodulatory agent therefore may require higher dosages to be effective, for example in murine models, a dose of 10mg/kg is widely used to investigate the anti-inflammatory and tissue-protective actions of melatonin (70)

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