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Annals Of The New York Academy Of Sciences 1989, 574: 57-59
In this paradigm, aquaporin 8 silencing, which is specifically expressed in IMM, enhances mitochondrial ROS generation and results in mitochondrial depolarization and cell death ( 2 O 2 at higher rates than complex I from mitochondria ( Peroxynitrite is a potent oxidant that is generated upon the reaction of superoxide with nitric oxide (NO)
