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163 Specifically, Dux, known for enhancing pluripotency during the transition from embryonic stem cells to 2-cell-like ESCs, induces H3K18la through a metabolic switch and p300 recruitment, boosting gene activation for pluripotency and epithelial cells and ultimately accelerating reprogramming efficiency

Human telomeres have a chromosome-specific length, characterised by ~ 515 kilobase pairs of tandem TTAGGG repeats and terminating in a shorter (50- to 400-nucleotide), single-stranded (ss) extension of the G-rich strand 4,5

61 demonstrated that NR supplementation altered the gut microbiome in mice and demonstrated that the gut microbiome change was able to impact weight gain in mice fed a high-fat diet