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Thus, the overall finding of this Report is clear: Cigarette smoking should be considered the most important of the known modifiable risk factors for coronary heart disease in the United States The first major prospective study results were made public in 1954 in the United States by Hammond and Horn and found a strong association between cigarette use among men and coronary heart disease (CHD)

HTPs are designed to heat tobacco instead of burning it, generating as a result a nicotine-containing aerosol with significantly lower levels of harmful chemicals compared with cigarette smoke

Tar is not one single chemical, instead it describes several chemicals that are in tobacco smoke

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